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Peptide record

TPDB63349

Cell-penetrating Peptides standard
48 amino acids
Basic Information
3D PDB MODEL
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TPDB63349
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 48-aa standard-residue cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
Sequence
PALFPWWWPFLRDVFTKGYGFGLGRKDANSYLGLYCINEKRRQRRRPQ
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C274H405N79O64S1
HM
R
5861.78
10.93
10
3
19
+7
2.38
-0.817
58.96
Mammalian: >20 hour Yeast: >20 hour E.coli: ?
20970
3.58
10
Residue Composition
number
2
A
7
R
2
N
2
D
1
C
1
E
2
Q
5
G
0
H
1
I
5
L
3
K
0
M
4
F
4
P
1
S
1
T
3
W
3
Y
1
V
Amino Acid Distribution
A: 2 R: 7 N: 2 D: 2 C: 1 E: 1 Q: 2 G: 5 H: 0 I: 1 L: 5 K: 3 M: 0 F: 4 P: 4 S: 1 T: 1 W: 3 Y: 3 V: 1
Chemical Descriptors
48 reviewed residue count
C274H405N79O64S1 sequence-only estimate (linear, free termini)
5861.78 sequence-only estimate (linear, free termini)
10.93 sequence-only estimate (linear, free termini)
+7 sequence-only estimate (linear, free termini)
2.38 sequence-only estimate (linear, free termini)
-0.817 sequence-only estimate (linear, free termini)
Evidence Records 1 records
Evidence 1 Activity

Source & Reference

CPPsite3.0

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.