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Peptide record

TPDB63312

Cell-penetrating Peptides standard
48 amino acids
Basic Information
3D PDB MODEL
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TPDB63312
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 48-aa standard-residue cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
Sequence
NLYSNSPENSPENLYSNSPENSPENLYSNSPENSPENLYSNSPENSPE
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C224H326N60O93
ARDCQGHIKMFTWV
NS
5347.40
2.78
0
8
8
-8
3.25
-1.717
32.50
Mammalian: 1.4 hour Yeast: 3 min E.coli: >10 hour
5960
1.11
28
Residue Composition
number
0
A
0
R
12
N
0
D
0
C
8
E
0
Q
0
G
0
H
0
I
4
L
0
K
0
M
0
F
8
P
12
S
0
T
0
W
4
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 12 D: 0 C: 0 E: 8 Q: 0 G: 0 H: 0 I: 0 L: 4 K: 0 M: 0 F: 0 P: 8 S: 12 T: 0 W: 0 Y: 4 V: 0
Chemical Descriptors
48 reviewed residue count
C224H326N60O93 sequence-only estimate (linear, free termini)
5347.40 sequence-only estimate (linear, free termini)
2.78 sequence-only estimate (linear, free termini)
-8 sequence-only estimate (linear, free termini)
3.25 sequence-only estimate (linear, free termini)
-1.717 sequence-only estimate (linear, free termini)
Evidence Records 1 records
Evidence 1 Activity

Source & Reference

CPPsite3.0

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.