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Peptide record

TPDB63305

SRAM C105Y Cell-penetrating Peptides standard
8 amino acids
Basic Information
3D PDB MODEL
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TPDB63305
SRAM C105Y
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CellPPD CellPPD-MOD CPPsite3.0 MLCPP 2.0 Peptipedia PerseuCPP
standard
No
A 8-aa standard natural cell-penetrating peptides peptide sequence curated from CellPPD, CellPPD-MOD, CPPsite3.0, and other sources, with an available 3D structural model.
C-terminal: Amidation N-terminal: Conjugation with fluorescein/FITC
Sequence
NKPILVFY-NH2
Physicochemical Analysis
C50H76N10O11
ARDCEQGHMSTW
NILKFPYV
993.21
9.74
1
0
5
+1
-1.01
0.625
133.75
Mammalian: 1.4 hour Yeast: 3 min E.coli: >10 hour
1490
150.02
2
Residue Composition
number
0
A
0
R
1
N
0
D
0
C
0
E
0
Q
0
G
0
H
1
I
1
L
1
K
0
M
1
F
1
P
0
S
0
T
0
W
1
Y
1
V
Amino Acid Distribution
A: 0 R: 0 N: 1 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 1 L: 1 K: 1 M: 0 F: 1 P: 1 S: 0 T: 0 W: 0 Y: 1 V: 1
Chemical Descriptors
8
C50H76N10O11
993.21
9.74
+1
-1.01
0.625
Amidation
L
Linear
Conjugation with fluorescein/FITC
N[C@@H](CC(=O)N)C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

HuH7 cells

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Protein derived
Fluorophore (fluorescein/ FITC)
Cytoplasm and nucleus, nucleolus
Very low
In vitro
CCCCCCCC
Additional Detail Fields 1 fields
CCCCCCCC