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Peptide record

TPDB63302

gHo Cell-penetrating Peptides Tumor-homing Peptides standard
12 amino acids
Basic Information
3D PDB MODEL
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TPDB63302
gHo
Cell-penetrating Peptides Tumor-homing Peptides
Cancer-related peptides Delivery and barrier-penetrating peptides
CellPPD-MOD CPPsite3.0 Peptipedia TumorHoPe2.0
standard
No
A 12-aa standard natural multi-activity (Cell-penetrating Peptides and Tumor-homing Peptides) peptide sequence curated from CellPPD-MOD, CPPsite3.0, Peptipedia, and other sources, with an available 3D structural model.
C-terminal: Amidated
Sequence
NHQQQNPHQPPM
Physicochemical Analysis
C60H90N22O19S1
ARDCEGILKFSTWYV
Q
1455.57
8.00
2
0
1
+0
6.20
-2.525
0.00
Mammalian: 1.4 hour Yeast: 3 min E.coli: >10 hour
0
0.00
6
Residue Composition
number
0
A
0
R
2
N
0
D
0
C
0
E
4
Q
0
G
2
H
0
I
0
L
0
K
1
M
0
F
3
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 2 D: 0 C: 0 E: 0 Q: 4 G: 0 H: 2 I: 0 L: 0 K: 0 M: 1 F: 0 P: 3 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
12
C60H90N22O19S1
1455.57
8.00
+0
6.20
-2.525
Amidated
Evidence Records 1 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Tumor cell
Homing
Glioma

Source & Reference

TumorHoPe2.0
TumorHoPe2
Peptide-based glioma-targeted drug delivery vector gHoPe2
2013
Elo Eriste et al. Bioconjug Chem. 2013 Mar 20 24(3):305-13.

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
U251 glioma cells, The human embryonic kidney 293 cell line (HEK 293), human glioma epithelial-like cell line U87 MG, cervical cancer HeLa cells
homozygous female nude mice (C.Cg/AnNTac-Foxn1nu, Taconic)
Phage display library
M13 phage display library
pVEC(LLIILRRRIRKQAHAHSK), doxorubicin
Additional Detail Fields 4 fields
pVEC(LLIILRRRIRKQAHAHSK), doxorubicin
U251 glioma cells, The human embryonic kidney 293 cell line (HEK 293), human glioma epithelial-like cell line U87 MG, cervical cancer HeLa cells
homozygous female nude mice (C.Cg/AnNTac-Foxn1nu, Taconic)
M13 phage display library