Back to search

Peptide record

TPDB63288

P22 N Cell-penetrating Peptides standard
19 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB63288
P22 N
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CellPPD CPPsite3.0 Peptipedia PerseuCPP
standard
No
A 19-aa standard natural cell-penetrating peptides peptide sequence curated from CellPPD, CPPsite3.0, Peptipedia, and other sources, with an available 3D structural model.
C-terminal: Conjugation with fluorescein by C-terminal Gly Cys amide
Sequence
NAKTRRHERRRKLAIERGC
Physicochemical Analysis
C95H172N42O26S1
DQMFPSWYV
R
2350.74
12.12
9
2
4
+6
10.96
-1.853
51.58
Mammalian: 1.4 hour Yeast: 3 min E.coli: >10 hour
0
0.00
3
Residue Composition
number
2
A
6
R
1
N
0
D
1
C
2
E
0
Q
1
G
1
H
1
I
1
L
2
K
0
M
0
F
0
P
0
S
1
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 2 R: 6 N: 1 D: 0 C: 1 E: 2 Q: 0 G: 1 H: 1 I: 1 L: 1 K: 2 M: 0 F: 0 P: 0 S: 0 T: 1 W: 0 Y: 0 V: 0
Chemical Descriptors
19
C95H172N42O26S1
2350.74
12.12
+6
10.96
-1.853
Conjugation with fluorescein by C-terminal Gly Cys amide
L
Cationic
Linear
Free
N[C@@H](CC(=O)N)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CC1=NC=NC1)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCCN=C)C(=O)NCC(=O)N[C@@H](CS)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

RAW 264.7

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L Cationic
Protein derived
Fluorophore (fluorescein)
Cytoplasm and nucleus
Moderate relative to Tat-(48–60) peptide
Non-endocytic mechanism
In vitro
CCCSSSSSGGGCCSCSCC
Additional Detail Fields 1 fields
CCCSSSSSGGGCCSCSCC