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Peptide record

TPDB63286

VP22 Cell-penetrating Peptides standard
32 amino acids
Basic Information
3D PDB MODEL
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TPDB63286
VP22
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 32-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
Sequence
NAATATRGRSAASRPTQRPRAPARSASRPRRP
Physicochemical Analysis
C138H243N61O42
DCEHILKMFWYV
R
3428.83
13.30
9
0
8
+9
10.13
-1.463
25.00
Mammalian: 1.4 hour Yeast: 3 min E.coli: >10 hour
0
0.00
9
Residue Composition
number
8
A
9
R
1
N
0
D
0
C
0
E
1
Q
1
G
0
H
0
I
0
L
0
K
0
M
0
F
5
P
4
S
3
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 8 R: 9 N: 1 D: 0 C: 0 E: 0 Q: 1 G: 1 H: 0 I: 0 L: 0 K: 0 M: 0 F: 0 P: 5 S: 4 T: 3 W: 0 Y: 0 V: 0
Chemical Descriptors
32
C138H243N61O42
3428.83
13.30
+9
10.13
-1.463
Free
L
Linear
Free
N[C@@H](CCSC)C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@H](CS)C(=O)N1CCC[C@H]1C(=O)NCC(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

Ai9 Tdtomato Npcs

Assay & Model

Ai9 or wild-type mice
Ai9 or wild-type mice

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
SpyCas9 RNPs
In vitro and in vivo
CCSCCCSSCSSSSCCTTCC
Additional Detail Fields 1 fields
CCSCCCSSCSSSSCCTTCC