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Peptide record

TPDB63282

PTD3 (M918) Cell-penetrating Peptides standard
22 amino acids
Basic Information
3D PDB MODEL
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TPDB63282
PTD3 (M918)
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 22-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
Sequence
MVTVLFRRLRIRRASGPPRVRV
Physicochemical Analysis
C116H207N43O25S1
NDCEQHKWY
R
2636.25
13.18
7
0
10
+7
4.17
-0.055
110.45
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
2
Residue Composition
number
1
A
7
R
0
N
0
D
0
C
0
E
0
Q
1
G
0
H
1
I
2
L
0
K
1
M
1
F
2
P
1
S
1
T
0
W
0
Y
4
V
Amino Acid Distribution
A: 1 R: 7 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 1 L: 2 K: 0 M: 1 F: 1 P: 2 S: 1 T: 1 W: 0 Y: 0 V: 4
Chemical Descriptors
22
C116H207N43O25S1
2636.25
13.18
+7
4.17
-0.055
Free
L
Linear
Free
N[C@@H](CC1=C(C(=NC1)C)CC)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1[nH]cnc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N[C@@H](CS)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](C)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

S. Aureus Infected Mac-T Or Hbmec Cell Lines , Ex Vivo Calvaria (Skull Cap)

Assay & Model

Femur injury model (Wistar rats (5 to 6 wks of age))
Femur injury model (Wistar rats (5 to 6 wks of age))

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Protein derived
Lysostaphin and LysK
In vitro and in vivo
CCSTHHHHHHHHHTCCHHHHHHHHTSSCC
Additional Detail Fields 1 fields
CCSTHHHHHHHHHTCCHHHHHHHHTSSCC