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Peptide record

TPDB63262

R8 Cell-penetrating Peptides standard
9 amino acids
Basic Information
3D PDB MODEL
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TPDB63262
R8
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 9-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
N-terminal: Conjugated with Snap-Tag
Sequence
MRRRRRRRR
Physicochemical Analysis
C53H107N33O10S1
ANDCEQGHILKFPSTWYV
R
1398.71
13.25
8
0
1
+8
6.25
-3.789
0.00
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
0
Residue Composition
number
0
A
8
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
0
L
0
K
1
M
0
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 8 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 0 M: 1 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
9
C53H107N33O10S1
1398.71
13.25
+8
6.25
-3.789
Free
L
Linear
Conjugated with Snap-Tag
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

Saos-2 Cells , HeLa And Sk-Hep-1 Cells

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Non-natural residues Linear L
Synthetic
Rho-labeled SNAP-tag (enzyme)
Cytosol
Nearly 5-fold higher than SNAP-Rho
Endocytosis
In vitro