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Peptide record

TPDB63252

MEK1 Cell-penetrating Peptides standard
13 amino acids
Basic Information
3D PDB MODEL
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TPDB63252
MEK1
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0 MLCPP 2.0 PerseuCPP
standard
No
A 13-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, MLCPP 2.0, and PerseuCPP, with an available 3D structural model.
Sequence
MPKKKPTPIQLNP
Physicochemical Analysis
C68H118N18O17S1
ARDCEGHFSWYV
P
1491.86
10.84
3
0
3
+3
4.81
-1.200
60.00
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
3
Residue Composition
number
0
A
0
R
1
N
0
D
0
C
0
E
1
Q
0
G
0
H
1
I
1
L
3
K
1
M
0
F
4
P
0
S
1
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 1 D: 0 C: 0 E: 0 Q: 1 G: 0 H: 0 I: 1 L: 1 K: 3 M: 1 F: 0 P: 4 S: 0 T: 1 W: 0 Y: 0 V: 0
Chemical Descriptors
13
C68H118N18O17S1
1491.86
10.84
+3
4.81
-1.200
Free
L
Linear
Free
N[C@@H](CCSC)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H]([C@@H](C)O)C(=O)N1CCC[C@H]1C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(=O)N)C(=O)N1CCC[C@H]1C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

HPASMC And HPAEC Cells

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Synthetic
In vitro
CTTCCSSSCCCCC
Additional Detail Fields 1 fields
CTTCCSSSCCCCC