Back to search

Peptide record

TPDB63227

RL2 Cell-penetrating Peptides standard
121 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB63227
RL2
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 121-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
Sequence
MNQKQPACHENDERPFYQKTAPYVPMYYVPNSYPYYGTNLYQRRPAIAINNPYVPRTYYANPAVVRPHAQIPQRQYLPNSHPPTVVRRPNLHPSFIAIPPKKIQDKIIIPTIGGSHHHHHH
Physicochemical Analysis
C646H969N187O168S3
W
P
14139.13
10.06
23
4
44
+10
26.31
-0.863
65.29
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
17880
126.46
39
Residue Composition
number
8
A
8
R
9
N
2
D
1
C
2
E
8
Q
3
G
10
H
10
I
3
L
5
K
2
M
2
F
20
P
4
S
5
T
0
W
12
Y
7
V
Amino Acid Distribution
A: 8 R: 8 N: 9 D: 2 C: 1 E: 2 Q: 8 G: 3 H: 10 I: 10 L: 3 K: 5 M: 2 F: 2 P: 20 S: 4 T: 5 W: 0 Y: 12 V: 7
Chemical Descriptors
121
C646H969N187O168S3
14139.13
10.06
+10
26.31
-0.863
Free
L
Cationic
Linear
Free
N[C@@H](CCCCN)C(=O)N[C@@H](CS)C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1[nH]cnc1)C(=O)N[C@@H](CS)C(=O)NCC(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

A549 And A431 Cells

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L Cationic
Protein derived
pDNA, siRNA, Non-coding RNA
Nucleus
Efficiently deliver Nucleic acids into the cells
In vitro
CCCCCSSSCC
Additional Detail Fields 1 fields
CCCCCSSSCC