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Peptide record

TPDB63225

Cell-penetrating Peptides standard
27 amino acids
Basic Information
3D PDB MODEL
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TPDB63225
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 27-aa standard-residue cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
Sequence
MLSLRQSIRFFKLLRLLRWWWRLLRLL
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C175H282N50O31S1
ANDCEGHPTYV
L
3614.54
13.10
7
0
17
+7
1.41
0.419
158.89
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
16500
4.56
3
Residue Composition
number
0
A
6
R
0
N
0
D
0
C
0
E
1
Q
0
G
0
H
1
I
10
L
1
K
1
M
2
F
0
P
2
S
0
T
3
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 6 N: 0 D: 0 C: 0 E: 0 Q: 1 G: 0 H: 0 I: 1 L: 10 K: 1 M: 1 F: 2 P: 0 S: 2 T: 0 W: 3 Y: 0 V: 0
Chemical Descriptors
27 reviewed residue count
C175H282N50O31S1 sequence-only estimate (linear, free termini)
3614.54 sequence-only estimate (linear, free termini)
13.10 sequence-only estimate (linear, free termini)
+7 sequence-only estimate (linear, free termini)
1.41 sequence-only estimate (linear, free termini)
0.419 sequence-only estimate (linear, free termini)
Evidence Records 1 records
Evidence 1 Activity

Source & Reference

CPPsite3.0

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.