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Peptide record

TPDB63222

Cytcox-Cys Cell-penetrating Peptides standard
13 amino acids
Basic Information
3D PDB MODEL
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TPDB63222
Cytcox-Cys
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 13-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
C-terminal: Amidation Chemical: Micelles
Sequence
MLSLRQSIRFFKC-NH2
Physicochemical Analysis
C73H121N21O17S2
ANDEGHPTWYV
RLFS
1629.01
11.32
3
0
6
+3
-0.71
0.315
90.00
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
4
Residue Composition
number
0
A
2
R
0
N
0
D
1
C
0
E
1
Q
0
G
0
H
1
I
2
L
1
K
1
M
2
F
0
P
2
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 2 N: 0 D: 0 C: 1 E: 0 Q: 1 G: 0 H: 0 I: 1 L: 2 K: 1 M: 1 F: 2 P: 0 S: 2 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
13
C73H121N21O17S2
1629.01
11.32
+3
-0.71
0.315
Amidation
Micelles
L
Linear
Free
N[C@@H](CCCN=C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC1=C(C(=NC1)C)CC)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CC1=CN=C(C)/C/1=C\C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1ccccc1)C(=O)NCC(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Assay & Model

Arabidopsis thaliana (A. thaliana)
Arabidopsis thaliana (A. thaliana)

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Protein derived
pDNA(pDONR-Cox2-RLuc, pATMTTF1, pDONR-35S-RLuc, and pDONR-35S-GFP)
For Cytcox- Mic (nuc-GFP), GFP fluorescence was not observed in root cells.
Direct translocation
In vivo
CCCCCSSSCCCCCCC
Additional Detail Fields 1 fields
CCCCCSSSCCCCCCC