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Peptide record

TPDB63221

MTS Cell-penetrating Peptides standard
12 amino acids
Basic Information
3D PDB MODEL
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TPDB63221
MTS
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 12-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
C-terminal: Amidation Chemical: Nanoparticle
Sequence
MLSLRQSIRFFK-NH2
Physicochemical Analysis
C70H116N20O16S1
ANDCEGHPTWYV
RLFS
1525.88
12.41
3
0
6
+3
-0.47
0.133
97.50
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
3
Residue Composition
number
0
A
2
R
0
N
0
D
0
C
0
E
1
Q
0
G
0
H
1
I
2
L
1
K
1
M
2
F
0
P
2
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 2 N: 0 D: 0 C: 0 E: 0 Q: 1 G: 0 H: 0 I: 1 L: 2 K: 1 M: 1 F: 2 P: 0 S: 2 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
12
C70H116N20O16S1
1525.88
12.41
+3
-0.47
0.133
Amidation
Nanoparticle
L
Linear
Free
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

HeLa Cells And Fibroblast Cells

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Non-natural residues Linear L
Synthetic
FITC-labeled pDNA (pCAG-GFP-ND)
Mitochondria
Low amount of labelled pND1 is quantified in the cytosolic fraction of HeLa cells
In vitro