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Peptide record

TPDB63216

Apo1–19PrP23–28 Cell-penetrating Peptides standard
25 amino acids
Basic Information
3D PDB MODEL
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TPDB63216
Apo1–19PrP23–28
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 25-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
Sequence
MKLLAMVALLVTICSLEGAKKRPKP
Physicochemical Analysis
C122H220N32O30S3
NDQHFWY
L
2711.47
10.55
5
1
13
+4
3.79
0.596
128.80
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
3
Residue Composition
number
3
A
1
R
0
N
0
D
1
C
1
E
0
Q
1
G
0
H
1
I
5
L
4
K
2
M
0
F
2
P
1
S
1
T
0
W
0
Y
2
V
Amino Acid Distribution
A: 3 R: 1 N: 0 D: 0 C: 1 E: 1 Q: 0 G: 1 H: 0 I: 1 L: 5 K: 4 M: 2 F: 0 P: 2 S: 1 T: 1 W: 0 Y: 0 V: 2
Chemical Descriptors
25
C122H220N32O30S3
2711.47
10.55
+4
3.79
0.596
Free
L
Linear
Free
N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(C)C)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

U87 or SH-SY5Y cells

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Chimeric
Aβ42–EGFP fusion protein expressing plasmid
Efficiently Internalized
In vitro
CCSSSCCCCHHHIIIIIHHHC
Additional Detail Fields 1 fields
CCSSSCCCCHHHIIIIIHHHC