Back to search

Peptide record

TPDB63215

cTP Cell-penetrating Peptides standard
31 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB63215
cTP
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 31-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
C-terminal: Amidation Chemical: FITC at C-terminus
Sequence
MKALQASIAYSFPISSPAASPRRFSRVIRAQ-NH2
Physicochemical Analysis
C152H248N46O41S1
NDCEGHTW
AS
3407.98
12.41
5
0
15
+5
1.65
0.000
79.03
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
1490
43.72
9
Residue Composition
number
6
A
4
R
0
N
0
D
0
C
0
E
2
Q
0
G
0
H
3
I
1
L
1
K
1
M
2
F
3
P
6
S
0
T
0
W
1
Y
1
V
Amino Acid Distribution
A: 6 R: 4 N: 0 D: 0 C: 0 E: 0 Q: 2 G: 0 H: 0 I: 3 L: 1 K: 1 M: 1 F: 2 P: 3 S: 6 T: 0 W: 0 Y: 1 V: 1
Chemical Descriptors
31
C152H248N46O41S1
3407.98
12.41
+5
1.65
0.000
Amidation
FITC at C-terminus
L
Amphipathic
Linear
Free
N[C@@H](CCSC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccccc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(=O)N)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

Triticum Aestivum Mesophyll Protoplasts

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L Amphipathic
Protein derived
DNase I
Chloroplast
More than 90% of the cells showed uptake of cT Pat a concentration of 10 μM
Direct translocation
In vitro
CCSCTTBSSSBCCSSCCCCCGGGGGGTTTCC
Additional Detail Fields 1 fields
CCSCTTBSSSBCCSSCCCCCGGGGGGTTTCC