Peptide record

TPDB63214

LYZ1–24PrP23–28 Cell-penetrating Peptides standard
30 amino acids
Basic Information
3D PDB MODEL
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TPDB63214
LYZ1–24PrP23–28
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 30-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
Sequence
MKALIVLGLVLLSVTVQGKVFERCKKRPKP
Physicochemical Analysis
C154H272N42O36S2
NDHWY
LKV
3352.23
11.08
7
1
14
+6
5.83
0.417
129.67
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
4
Residue Composition
number
1
A
2
R
0
N
0
D
1
C
1
E
1
Q
2
G
0
H
1
I
5
L
5
K
1
M
1
F
2
P
1
S
1
T
0
W
0
Y
5
V
Amino Acid Distribution
A: 1 R: 2 N: 0 D: 0 C: 1 E: 1 Q: 1 G: 2 H: 0 I: 1 L: 5 K: 5 M: 1 F: 1 P: 2 S: 1 T: 1 W: 0 Y: 0 V: 5
Chemical Descriptors
30
C154H272N42O36S2
3352.23
11.08
+6
5.83
0.417
Free
L
Linear
Free
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

U87 or SH-SY5Y cells

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Non-natural residues Linear L
Chimeric
Aβ42–EGFP fusion protein expressing plasmid
Efficiently Internalized
In vitro