TPDB

3D PDB MODEL

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TPDB ID TPDB63177

Activity

Cell-penetrating Peptides

Activity_category_statistics

Delivery and barrier-penetrating peptides

Database_Source

CPPsite3.0

Sequence_Type

standard

Has_Modification No

Description A 25-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.

Sequence

MIASHLLAYFFTELNKVLKQRAKKK

FASTA

>TPDB63177|Cell-penetrating Peptides|length=25
MIASHLLAYFFTELNKVLKQRAKKK

Formula C139H229N37O33S1

Absent Amino Acids DCGPW

Common Amino Acids K

Mass 2978.64

PI 10.76

Basic Residues 7

Acidic Residues 1

Hydrophobic Residues 13

Net Charge +5

Boman Index 3.59

Hydrophobicity -0.148

Aliphatic Index 101.60

Half Life

Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour

Extinction Coefficient Cystines 1490

Absorbance 280nm 50.02

Polar Residues 5

number

3

A

1

R

1

N

0

D

0

C

1

E

1

Q

0

G

1

H

1

I

4

L

5

K

1

M

2

F

0

P

1

S

1

T

0

W

1

Y

1

V

Amino Acid Distribution

A: 3 R: 1 N: 1 D: 0 C: 0 E: 1 Q: 1 G: 0 H: 1 I: 1 L: 4 K: 5 M: 1 F: 2 P: 0 S: 1 T: 1 W: 0 Y: 1 V: 1

Length

25

Formula

C139H229N37O33S1

Mass

2978.64

PI

10.76

Net Charge

+5

Boman Index

3.59

Hydrophobicity

-0.148

Evidence 1 Activity

Source & Reference

Database Source CPPsite3.0

Other

Source Activity Label	Source Definition
Cell-penetrating Peptides	CPPsite3.0 experimentally validated cell-penetrating peptide annotation.