Back to search

Peptide record

TPDB63170

RB1 Cell-penetrating Peptides standard
39 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB63170
RB1
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 39-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
C-terminal: Amidation N-terminal: Acetylation
Sequence
Ac-MGRKKRRQRRRPPQAPGIMLRRLQKGNLPVSRYPYDVPD-NH2
Physicochemical Analysis
C203H345N73O51S2
CEHFTW
R
4688.55
12.31
12
2
11
+10
13.38
-1.474
57.44
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
2980
63.56
7
Residue Composition
number
1
A
9
R
1
N
2
D
0
C
0
E
3
Q
3
G
0
H
1
I
3
L
3
K
2
M
0
F
6
P
1
S
0
T
0
W
2
Y
2
V
Amino Acid Distribution
A: 1 R: 9 N: 1 D: 2 C: 0 E: 0 Q: 3 G: 3 H: 0 I: 1 L: 3 K: 3 M: 2 F: 0 P: 6 S: 1 T: 0 W: 0 Y: 2 V: 2
Chemical Descriptors
39
C203H345N73O51S2
4688.55
12.31
+10
13.38
-1.474
Amidation
L
Linear
Acetylation
NCC(=O)N[C@@H](C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(=O)O)C(=O)NCC(=O)NCC(=O)NCC(=O)NCC(=O)NCC(=O)NCC(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC1=C(C(=NC1)C)CC)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CS)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

Acute Brain Slices Of Mice

Assay & Model

Male C57Bl/6 mice
Male C57Bl/6 mice

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Synthetic
In vivo and ex vivo
CTTHHHHHHHHHTTTBTTSSSTTTTCSCCCBCCCGGGCC
Additional Detail Fields 1 fields
CTTHHHHHHHHHTTTBTTSSSTTTTCSCCCBCCCGGGCC