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Peptide record

TPDB63166

Peptide 2 Cell-penetrating Peptides standard
23 amino acids
Basic Information
3D PDB MODEL
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TPDB63166
Peptide 2
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CellPPD CellPPD-MOD CPPsite3.0 MLCPP 2.0 Peptipedia PerseuCPP
standard
No
A 23-aa standard natural cell-penetrating peptides peptide sequence curated from CellPPD, CellPPD-MOD, CPPsite3.0, and other sources, with an available 3D structural model.
C-terminal: Cysteamide group N-terminal: Acetylation
Sequence
Ac-MGLGLHLLVLAAALQGAKKKRKV
Physicochemical Analysis
C110H199N33O25S1
NDCEIFPSTWY
L
2416.06
11.80
6
0
13
+5
2.21
0.535
144.35
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
1
Residue Composition
number
4
A
1
R
0
N
0
D
0
C
0
E
1
Q
3
G
1
H
0
I
6
L
4
K
1
M
0
F
0
P
0
S
0
T
0
W
0
Y
2
V
Amino Acid Distribution
A: 4 R: 1 N: 0 D: 0 C: 0 E: 0 Q: 1 G: 3 H: 1 I: 0 L: 6 K: 4 M: 1 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 2
Chemical Descriptors
23
C110H199N33O25S1
2416.06
11.80
+5
2.21
0.535
Cysteamide group
L
Amphipathic
Linear
Acetylation
N[C@@H](CCSC)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC1=NC=NC1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(=O)N)C(=O)NCC(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C(C)C)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

HS-68 Cells

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L Amphipathic
Chimeric
Nucleus
Non-endocytic pathway (direct translocation)
In vitro
CCCCCSHHHHHHHTCCTTCCCC
Additional Detail Fields 1 fields
CCCCCSHHHHHHHTCCTTCCCC