Back to search

Peptide record

TPDB63161

Cell-penetrating Peptides standard
31 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB63161
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 31-aa standard-residue cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
Sequence
MERKKRRRESWVHLPPPVHLPPPGGHHHHHH
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C169H256N62O37S1
ANDCQIFTY
H
3780.35
11.96
14
2
6
+5
3.25
-1.697
43.87
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
5500
1.45
1
Residue Composition
number
0
A
4
R
0
N
0
D
0
C
2
E
0
Q
2
G
8
H
0
I
2
L
2
K
1
M
0
F
6
P
1
S
0
T
1
W
0
Y
2
V
Amino Acid Distribution
A: 0 R: 4 N: 0 D: 0 C: 0 E: 2 Q: 0 G: 2 H: 8 I: 0 L: 2 K: 2 M: 1 F: 0 P: 6 S: 1 T: 0 W: 1 Y: 0 V: 2
Chemical Descriptors
31 reviewed residue count
C169H256N62O37S1 sequence-only estimate (linear, free termini)
3780.35 sequence-only estimate (linear, free termini)
11.96 sequence-only estimate (linear, free termini)
+5 sequence-only estimate (linear, free termini)
3.25 sequence-only estimate (linear, free termini)
-1.697 sequence-only estimate (linear, free termini)
Evidence Records 1 records
Evidence 1 Activity

Source & Reference

CPPsite3.0

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.