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Peptide record

TPDB63156

Crot(27-39) derivative (2) (CPP52) Cell-penetrating Peptides standard
12 amino acids
Basic Information
3D PDB MODEL
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TPDB63156
Crot(27-39) derivative (2) (CPP52)
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CellPPD CPPsite3.0 Peptipedia PerseuCPP
standard
No
A 12-aa standard natural cell-penetrating peptides peptide sequence curated from CellPPD, CPPsite3.0, Peptipedia, and other sources, with an available 3D structural model.
C-terminal: Conjugated with TAMRA
Sequence
MDCRWRWKCCKK
Physicochemical Analysis
C70H111N23O15S4
ANEQGHILFPSTYV
CK
1643.04
9.82
5
1
3
+4
1.17
-1.383
0.00
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
11125
677.10
3
Residue Composition
number
0
A
2
R
0
N
1
D
3
C
0
E
0
Q
0
G
0
H
0
I
0
L
3
K
1
M
0
F
0
P
0
S
0
T
2
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 2 N: 0 D: 1 C: 3 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 3 M: 1 F: 0 P: 0 S: 0 T: 0 W: 2 Y: 0 V: 0
Chemical Descriptors
12
C70H111N23O15S4
1643.04
9.82
+4
1.17
-1.383
Conjugated with TAMRA
L
Linear
Free
NCC(=O)N[C@@H]([C@@H](C)CC)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1[nH]cnc1)C(=O)N[C@@H](CO)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC1=C(C(=NC1)C)CC)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](C(C)C)C(=O)NCC(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CS)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

E. Coli Dh5Α

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
TAMRA dye
Cytoplasm
Penetration efficiency- 57.7265566666667A.U.
In vitro
CGGGTSSSTTHHHHTGGGSSCC
Additional Detail Fields 1 fields
CGGGTSSSTTHHHHTGGGSSCC