Peptide record

TPDB63150

AA8H Cell-penetrating Peptides standard
10 amino acids
Basic Information
3D PDB MODEL
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TPDB63150
AA8H
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 10-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
N-terminal: Conjugated with FITC
Sequence
MAWWKSWIEQ
Physicochemical Analysis
C66H89N15O15S1
RNDCGHLFPTYV
W
1364.58
6.94
1
1
6
-0
-2.54
-0.620
49.00
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
16500
1209.16
2
Residue Composition
number
1
A
0
R
0
N
0
D
0
C
1
E
1
Q
0
G
0
H
1
I
0
L
1
K
1
M
0
F
0
P
1
S
0
T
3
W
0
Y
0
V
Amino Acid Distribution
A: 1 R: 0 N: 0 D: 0 C: 0 E: 1 Q: 1 G: 0 H: 0 I: 1 L: 0 K: 1 M: 1 F: 0 P: 0 S: 1 T: 0 W: 3 Y: 0 V: 0
Chemical Descriptors
10
C66H89N15O15S1
1364.58
6.94
-0
-2.54
-0.620
Free
L
Linear
Conjugated with FITC
N[C@@H](CCSC)C(=O)N[C@@H](C)C(=O)N[C@@H](CC1=CN=C(C)/C/1=C\C)C(=O)N[C@@H](CC1=CN=C(C)/C/1=C\C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC1=C(C(=NC1)C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCC(=O)N)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

HeLa Cells

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Protein derived
Intracellular translocation uptake efficiency at 1μM in the order of AA3H> AA5H> AA8H> AA13H> AA4H
In vitro
CCHHHHTTCC
Additional Detail Fields 1 fields
CCHHHHTTCC