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Peptide record

TPDB63149

AA4H Cell-penetrating Peptides standard
10 amino acids
Basic Information
3D PDB MODEL
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TPDB63149
AA4H
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 10-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
N-terminal: Conjugated with FITC
Sequence
MATKGGTVKA
Physicochemical Analysis
C40H74N12O13S1
RNDCEQHILFPSWY
AGKT
963.16
10.60
2
0
4
+2
1.78
-0.030
49.00
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
2
Residue Composition
number
2
A
0
R
0
N
0
D
0
C
0
E
0
Q
2
G
0
H
0
I
0
L
2
K
1
M
0
F
0
P
0
S
2
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 2 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 2 H: 0 I: 0 L: 0 K: 2 M: 1 F: 0 P: 0 S: 0 T: 2 W: 0 Y: 0 V: 1
Chemical Descriptors
10
C40H74N12O13S1
963.16
10.60
+2
1.78
-0.030
Free
L
Linear
Conjugated with FITC
N[C@@H](CCSC)C(=O)N[C@@H](C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)NCC(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

HeLa Cells

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Protein derived
Intracellular translocation uptake efficiency at 1μM in the order of AA3H> AA5H> AA8H> AA13H> AA4H
In vitro
CTTTTCCCCC
Additional Detail Fields 1 fields
CTTTTCCCCC