Back to search

Peptide record

TPDB63148

TTR1–21PrP23–28 Cell-penetrating Peptides standard
27 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB63148
TTR1–21PrP23–28
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 27-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
Sequence
MASLRLFLLCLAGLVFVSEAGKKRPKP
Physicochemical Analysis
C136H230N36O32S2
NDQHITWY
L
2945.66
10.82
5
1
14
+4
1.33
0.622
119.26
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
3
Residue Composition
number
3
A
2
R
0
N
0
D
1
C
1
E
0
Q
2
G
0
H
0
I
6
L
3
K
1
M
2
F
2
P
2
S
0
T
0
W
0
Y
2
V
Amino Acid Distribution
A: 3 R: 2 N: 0 D: 0 C: 1 E: 1 Q: 0 G: 2 H: 0 I: 0 L: 6 K: 3 M: 1 F: 2 P: 2 S: 2 T: 0 W: 0 Y: 0 V: 2
Chemical Descriptors
27
C136H230N36O32S2
2945.66
10.82
+4
1.33
0.622
Free
L
Linear
Free
N[C@@H](C)C(=O)NCC(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(C)C)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

U87 or SH-SY5Y cells

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Chimeric
Aβ42–EGFP fusion protein expressing plasmid
Efficiently Internalized
In vitro
CCSCTTCSTTHHHHHTTTTCC
Additional Detail Fields 1 fields
CCSCTTCSTTHHHHHTTTTCC