Peptide record

TPDB63146

AAH3 (compound 60) AAH3 (compound 66) AAH3 (compound 72) Cell-penetrating Peptides modified_plain modified
10 amino acids
Basic Information
3D PDB MODEL
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Standard-residue backbone model; source-recorded chemical modifications are not verified in these coordinates.

TPDB63146
AAH3 (compound 60) AAH3 (compound 66) AAH3 (compound 72)
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
modified_plain
Yes
A 10-aa modified cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
C-terminal: Amidation N-terminal: Acylation
Sequence
MASIWVGHRG-NH2
Physicochemical Analysis

Sequence-only estimates are not provided for modified or non-standard source notation. Reported molecular properties, when available, are retained below with their source records.

Chemical Descriptors
10 reviewed residue count
Amidation Activity
L Activity
Linear Activity
Acylation Activity
N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)O Activity
Evidence Records 3 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

Human THP-1 Monocyte-Like Cell Line

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Linear 9mer 3,5 difluorophenylglycine
In vitro
CCCCCCCCC
Evidence 2 Activity

Activity

Cell-penetrating Peptides

Target

Human THP-1 Monocyte-Like Cell Line

Source & Reference

CPPsite3.0
CPPsite3

Other

Natural residues Linear L
7-mer cyclic lactam
In vitro
CCCCCCCCC
Evidence 3 Activity

Activity

Cell-penetrating Peptides

Target

Human THP-1 Monocyte-Like Cell Line

Source & Reference

CPPsite3.0
CPPsite3

Other

Natural residues Linear L
Triazole
In vitro
CCCCCCCCC
Additional Detail Fields 1 fields
CCCCCCCCC