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Peptide record

TPDB63138

I4A Cell-penetrating Peptides standard
10 amino acids
Basic Information
3D PDB MODEL
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TPDB63138
I4A
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 10-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
N-terminal: Conjugated with FITC
Sequence
MASAWVGHRG
Physicochemical Analysis
C46H70N16O12S1
NDCEQILKFPTY
AG
1071.22
11.05
2
0
5
+1
-0.43
-0.050
49.00
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
5500
513.43
1
Residue Composition
number
2
A
1
R
0
N
0
D
0
C
0
E
0
Q
2
G
1
H
0
I
0
L
0
K
1
M
0
F
0
P
1
S
0
T
1
W
0
Y
1
V
Amino Acid Distribution
A: 2 R: 1 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 2 H: 1 I: 0 L: 0 K: 0 M: 1 F: 0 P: 0 S: 1 T: 0 W: 1 Y: 0 V: 1
Chemical Descriptors
10
C46H70N16O12S1
1071.22
11.05
+1
-0.43
-0.050
Free
L
Linear
Conjugated with FITC
N[C@@H](CCSC)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N[C@@H](C)C(=O)N[C@@H](CC1=C(C(=NC1)C)CC)C(=O)N[C@@H](C(C)C)C(=O)NCC(=O)N[C@@H](CC1=NC=NC1)C(=O)N[C@@H](CCCN=C)C(=O)NCC(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

HeLa Cells

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Synthetic
FITC dye
Relatively low uptake
In vitro
CCCCCSCCC
Additional Detail Fields 1 fields
CCCCCSCCC