Back to search

Peptide record

TPDB63130

IRF5-CPP9 mPrP1-28 Cell-penetrating Peptides standard
28 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB63130
IRF5-CPP9 mPrP1-28
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CellPPD CellPPD-MOD CPPsite3.0 MLCPP 2.0 Peptipedia PerseuCPP
standard
No
A 28-aa standard natural cell-penetrating peptides peptide sequence curated from CellPPD, CellPPD-MOD, CPPsite3.0, and other sources, with an available 3D structural model.
Sequence
MANLGYWLLALFVTMWTDVGLCKKRPKP
Physicochemical Analysis
C153H239N37O35S3
EQHIS
L
3252.99
10.07
4
1
15
+3
-2.84
0.300
97.50
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
12490
383.95
5
Residue Composition
number
2
A
1
R
1
N
1
D
1
C
0
E
0
Q
2
G
0
H
0
I
5
L
3
K
2
M
1
F
2
P
0
S
2
T
2
W
1
Y
2
V
Amino Acid Distribution
A: 2 R: 1 N: 1 D: 1 C: 1 E: 0 Q: 0 G: 2 H: 0 I: 0 L: 5 K: 3 M: 2 F: 1 P: 2 S: 0 T: 2 W: 2 Y: 1 V: 2
Chemical Descriptors
28
C153H239N37O35S3
3252.99
10.07
+3
-2.84
0.300
Free
L
Linear
Free
N[C@@H](CCSC)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC1=C(C(=NC1)C)CC)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CC1=C(C(=NC1)C)CC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](C(C)C)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCN=C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)O
Evidence Records 2 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

HeLa, N2A, Ng108-15

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Non-natural residues Linear L
Protein derived
Alexa Fluor 488 or BODIPY FL
Lysosomes
Lipid raft-dependent macropinocytosis
In vitro
Evidence 2 Activity

Activity

Cell-penetrating Peptides

Target

PBMCs, Cd19+ B Cells, Cd14+ Monocytes, And Bdca2+Cd123+ Plasmacytoid Dendritic Cells (Pdcs), HeLa And THP-1 Cells

Source & Reference

CPPsite3.0
CPPsite3

Other

Natural residues Linear L
Chimeric
FITC dye
In vitro
CCCTTHHHHHHHHHTTSSSSSSCCCCCC
Additional Detail Fields 1 fields
CCCTTHHHHHHHHHTTSSSSSSCCCCCC