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Peptide record

TPDB63123

TCTP(I-9) I2A subsetution mutant Cell-penetrating Peptides standard
9 amino acids
Basic Information
3D PDB MODEL
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TPDB63123
TCTP(I-9) I2A subsetution mutant
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CellPPD CellPPD-MOD CPPsite3.0 MLCPP 2.0 Peptipedia
standard
No
A 9-aa standard natural cell-penetrating peptides peptide sequence curated from CellPPD, CellPPD-MOD, CPPsite3.0, and other sources, with an available 3D structural model.
C-terminal: Amidation N-terminal: Conjugation with rhodamine B
Sequence
MAIYRDLIS-NH2
Physicochemical Analysis
C48H80N12O14S1
NCEQGHKFPTWV
I
1081.30
6.71
1
1
6
-0
-0.35
0.711
141.11
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
1490
137.80
2
Residue Composition
number
1
A
1
R
0
N
1
D
0
C
0
E
0
Q
0
G
0
H
2
I
1
L
0
K
1
M
0
F
0
P
1
S
0
T
0
W
1
Y
0
V
Amino Acid Distribution
A: 1 R: 1 N: 0 D: 1 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 2 L: 1 K: 0 M: 1 F: 0 P: 0 S: 1 T: 0 W: 0 Y: 1 V: 0
Chemical Descriptors
9
C48H80N12O14S1
1081.30
6.71
-0
-0.35
0.711
Amidation
L
Linear
Conjugation with rhodamine B
N[C@@H](CCSC)C(=O)N[C@@H](C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

HeLa

Source & Reference

CPPsite3.0
CPPsite3
US 20100168034

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Protein derived
Fluorophore (Rhodamine)
In vitro
CCTHHHHCC
Additional Detail Fields 1 fields
CCTHHHHCC