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Peptide record

TPDB63122

SN25-2 (CPP6) Cell-penetrating Peptides standard
11 amino acids
Basic Information
3D PDB MODEL
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TPDB63122
SN25-2 (CPP6)
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 11-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
Sequence
MAISGGFIRRV
Physicochemical Analysis
C53H91N17O13S1
NDCEQHLKPTWY
RGI
1206.47
12.40
2
0
6
+2
-0.31
0.827
106.36
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
1
Residue Composition
number
1
A
2
R
0
N
0
D
0
C
0
E
0
Q
2
G
0
H
2
I
0
L
0
K
1
M
1
F
0
P
1
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 1 R: 2 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 2 H: 0 I: 2 L: 0 K: 0 M: 1 F: 1 P: 0 S: 1 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
11
C53H91N17O13S1
1206.47
12.40
+2
-0.31
0.827
Free
L
Linear
Free
N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCN=C)C(=O)NCC(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCCCN)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

B16-F10 Cells , PC-12 Cells ,B16-F10 And Human Dermal Fibroblasts (Hdfs)

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Protein derived
FITC at N terminal
CPP-6 displayed the highest cellular uptake at 71.9%
In vitro
CCCCCCCSSSCCCCC
Additional Detail Fields 1 fields
CCCCCCCSSSCCCCC