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Peptide record

TPDB63110

SVM4 Blood-Brain Barrier Cell-penetrating Peptides standard
19 amino acids
Basic Information
3D PDB MODEL
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TPDB63110
SVM4
Blood-Brain Barrier Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
BBPpredict CPPsite3.0
standard
No
A 19-aa standard natural multi-activity (Blood-Brain Barrier and Cell-penetrating Peptides) peptide sequence curated from BBPpredict and CPPsite3.0, with an available 3D structural model.
N-terminal: Conjugated with Cyanine5.5 (Cy5.5)
Sequence
LYKKGPAKKGRPPLRGWFH
Physicochemical Analysis
C107H166N32O21
NDCEQIMSTV
K
2236.70
11.65
7
0
6
+6
2.71
-1.253
46.32
Mammalian: 5.5 hour Yeast: 3 min E.coli: 2 min
6990
312.51
1
Residue Composition
number
1
A
2
R
0
N
0
D
0
C
0
E
0
Q
3
G
1
H
0
I
2
L
4
K
0
M
1
F
3
P
0
S
0
T
1
W
1
Y
0
V
Amino Acid Distribution
A: 1 R: 2 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 3 H: 1 I: 0 L: 2 K: 4 M: 0 F: 1 P: 3 S: 0 T: 0 W: 1 Y: 1 V: 0
Chemical Descriptors
19
C107H166N32O21
2236.70
11.65
+6
2.71
-1.253
Free
L
Amphipathic
Linear
Conjugated with Cyanine5.5 (Cy5.5)
N1CCC[C@H]1C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)NCC(=O)N[C@H]1CC(=O)OOC(=O)[C@H]2N(C1=O)CCC2
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

Primary Human Astrocytes

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L Amphipathic
Synthetic
Cy5.5 dye
In vitro
CGGGTTTTSSCC
Additional Detail Fields 1 fields
CGGGTTTTSSCC