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Peptide record

TPDB63102

BBA-CPP9 (peptide 21) Cell-penetrating Peptides modified_plain modified
12 amino acids
Basic Information
3D PDB MODEL
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Standard-residue backbone model; source-recorded chemical modifications are not verified in these coordinates.

TPDB63102
BBA-CPP9 (peptide 21)
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
modified_plain
Yes
A 12-aa modified cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
C-terminal: Conjugated with FAM via MiniPEG-Lys Linker N-terminal: Acetylation
Sequence
Ac-LTFCHYWCQLTS
Physicochemical Analysis

Sequence-only estimates are not provided for modified or non-standard source notation. Reported molecular properties, when available, are retained below with their source records.

Chemical Descriptors
12 reviewed residue count
Conjugated with FAM via MiniPEG-Lys Linker Activity
L Activity
Linear Activity
Acetylation Activity
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

Sjsa-1 Cells, HeLa Cells , Sw480 Cells

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Non-natural residues Linear L
Synthetic
FAM dye
Cytoplasm and nucleus
Cells treated with peptides 21, 23, or 25 were brightly fluorescent, showing a combination of punctate and diffuse fluorescence signals in HeLa cells and with the latter being throughout the entire cell volume including the nucleus.
In vitro