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Peptide record

TPDB63088

CorTS 1 Cell-penetrating Peptides standard
11 amino acids
Basic Information
3D PDB MODEL
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TPDB63088
CorTS 1
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 11-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
C-terminal: Amidation
Sequence
LRRLRLRRNRL-NH2
Physicochemical Analysis
C64H124N30O13
ADCEQGHIKMFPSTWYV
R
1521.88
13.10
6
0
4
+6
3.04
-1.391
141.82
Mammalian: 5.5 hour Yeast: 3 min E.coli: 2 min
0
0.00
1
Residue Composition
number
0
A
6
R
1
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
4
L
0
K
0
M
0
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 6 N: 1 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 4 K: 0 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
11
C64H124N30O13
1521.88
13.10
+6
3.04
-1.391
Amidation
L
Linear
Free
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

HCE cells and goat eyes

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Non-natural residues Linear L
Synthetic
FITC and β-galactosidase
Cytoplasm
Dose dependent cellular uptake
Endocytosis
In vitro and ex vivo