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Peptide record

TPDB63083

peptide 17 Cell-penetrating Peptides standard
10 amino acids
Basic Information
3D PDB MODEL
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TPDB63083
peptide 17
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 10-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
Sequence
LRLKKYKVPQ
Physicochemical Analysis
C60H105N17O13
ANDCEGHIMFSTW
K
1272.60
10.91
4
0
4
+4
2.82
-1.080
107.00
Mammalian: 5.5 hour Yeast: 3 min E.coli: 2 min
1490
117.08
2
Residue Composition
number
0
A
1
R
0
N
0
D
0
C
0
E
1
Q
0
G
0
H
0
I
2
L
3
K
0
M
0
F
1
P
0
S
0
T
0
W
1
Y
1
V
Amino Acid Distribution
A: 0 R: 1 N: 0 D: 0 C: 0 E: 0 Q: 1 G: 0 H: 0 I: 0 L: 2 K: 3 M: 0 F: 0 P: 1 S: 0 T: 0 W: 0 Y: 1 V: 1
Chemical Descriptors
10
C60H105N17O13
1272.60
10.91
+4
2.82
-1.080
Free
L
Linear
Free
N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

HeLa Cells And J774.2 Mouse Macrophage Cell Lines.

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Synthetic
5-FAM at N terminal
Cytoplasm
All the peptides tested were internalised into the cells
Endocytosis
In vitro
CCSSTTCC
Additional Detail Fields 1 fields
CCSSTTCC