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Peptide record

TPDB63055

TP15 Cell-penetrating Peptides standard
19 amino acids
Basic Information
3D PDB MODEL
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TPDB63055
TP15
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CellPPD CellPPD-MOD CPPsite3.0 Peptipedia PerseuCPP
standard
No
A 19-aa standard natural cell-penetrating peptides peptide sequence curated from CellPPD, CellPPD-MOD, CPPsite3.0, and other sources, with an available 3D structural model.
N-terminal: Biotinylation at amino group of Lys
Sequence
LNSAGYLLGKLKALAALAK
Physicochemical Analysis
C89H155N23O23
RDCEQHIMFPTWV
L
1915.35
10.46
3
0
12
+3
-1.61
0.721
149.47
Mammalian: 5.5 hour Yeast: 3 min E.coli: 2 min
1490
77.79
3
Residue Composition
number
5
A
0
R
1
N
0
D
0
C
0
E
0
Q
2
G
0
H
0
I
6
L
3
K
0
M
0
F
0
P
1
S
0
T
0
W
1
Y
0
V
Amino Acid Distribution
A: 5 R: 0 N: 1 D: 0 C: 0 E: 0 Q: 0 G: 2 H: 0 I: 0 L: 6 K: 3 M: 0 F: 0 P: 0 S: 1 T: 0 W: 0 Y: 1 V: 0
Chemical Descriptors
19
C89H155N23O23
1915.35
10.46
+3
-1.61
0.721
Free
L
Amphipathic
Linear
Biotinylation at amino group of Lys
N[C@@H](CC(C)C)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CO)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

Human bowes melanoma cells

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L Amphipathic
Chimeric
Biotin
Cytoplasm and nucleus and intracellular membranous structures
Very low relative to Transportan
Non-receptor mediated endocytosis
In vitro
CCCTTSHHHHHHHHHHHCC
Additional Detail Fields 1 fields
CCCTTSHHHHHHHHHHHCC