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Peptide record

TPDB63016

PepFect 32 Cell-penetrating Peptides modified_plain modified
33 amino acids
Basic Information
3D PDB MODEL
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TPDB63016
PepFect 32
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
modified_plain
Yes
A 33-aa modified cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
C-terminal: Amidation N-terminal: Stearylation
Sequence
LLOOLAAAALOOLLTFFYGGSRGKRNNFKTEEY-NH2
Physicochemical Analysis
C152H235N39O41
DCQHIMPWV
L
3264.77
9.97
4
2
15
+2
-0.39
0.048
83.03
Mammalian: 5.5 hour Yeast: 3 min E.coli: 2 min
2980
91.28
7
Residue Composition
number
4
A
2
R
2
N
0
D
0
C
2
E
0
Q
3
G
0
H
0
I
6
L
2
K
0
M
3
F
0
P
1
S
2
T
0
W
2
Y
0
V
Amino Acid Distribution
A: 4 R: 2 N: 2 D: 0 C: 0 E: 2 Q: 0 G: 3 H: 0 I: 0 L: 6 K: 2 M: 0 F: 3 P: 0 S: 1 T: 2 W: 0 Y: 2 V: 0
Chemical Descriptors
33
C152H235N39O41
3264.77
9.97
+2
-0.39
0.048
Amidation
Modified
Amphipathic
Linear
Stearylation
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

U87 Mg-Luc2 And HeLa-Luc Cell Lines

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Non-natural residues Linear Modified Amphipathic
Synthetic
Double-stranded siRNA luc
Cytosol
Did not improve the efficacy of the parent peptide PF14
In vitro