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Peptide record

TPDB63015

Pepfect 14 Cell-penetrating Peptides modified_plain modified
14 amino acids
Basic Information
3D PDB MODEL
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TPDB63015
Pepfect 14
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
modified_plain
Yes
A 14-aa modified cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
C-terminal: Amidation Chemical: O, Ornithine N-terminal: Stearylation
Sequence
LLOOLAAAALOOLL-NH2
Physicochemical Analysis
C48H88N10O11
RNDCEQGHIKMFPSTWYV
L
981.29
6.02
0
0
10
-0
-4.04
2.143
195.71
Mammalian: 5.5 hour Yeast: 3 min E.coli: 2 min
0
0.00
0
Residue Composition
number
4
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
6
L
0
K
0
M
0
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 4 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 6 K: 0 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
14
C48H88N10O11
981.29
6.02
-0
-4.04
2.143
Amidation
O, Ornithine
Modified
Amphipathic
Linear
Stearylation
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

Hela, Luciferase stable BHK21 cells

Source & Reference

CPPsite3.0
CPPsite3
US 2014/0140929 A1

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Non-natural residues Linear Modified Amphipathic
Synthetic
Nucleic acid (SCO and siRNA)
Endocytosis
In vitro