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Peptide record

TPDB63002

Shuttle85 (S85) Cell-penetrating Peptides standard
25 amino acids
Basic Information
3D PDB MODEL
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TPDB63002
Shuttle85 (S85)
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 25-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
Sequence
LLKIWSRLIKIWTQGRRLGARAQAR
Physicochemical Analysis
C136H232N46O30
NDCEHMFPYV
R
2991.63
13.01
7
0
12
+7
0.10
-0.292
121.20
Mammalian: 5.5 hour Yeast: 3 min E.coli: 2 min
11000
367.69
4
Residue Composition
number
3
A
5
R
0
N
0
D
0
C
0
E
2
Q
2
G
0
H
3
I
4
L
2
K
0
M
0
F
0
P
1
S
1
T
2
W
0
Y
0
V
Amino Acid Distribution
A: 3 R: 5 N: 0 D: 0 C: 0 E: 0 Q: 2 G: 2 H: 0 I: 3 L: 4 K: 2 M: 0 F: 0 P: 0 S: 1 T: 1 W: 2 Y: 0 V: 0
Chemical Descriptors
25
C136H232N46O30
2991.63
13.01
+7
0.10
-0.292
Free
L
Amphiphilic
Linear
Free
N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC1=CN=C(C)/C/1=C\C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC1=CN=C(C)/C/1=C\C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCC(=O)N)C(=O)NCC(=O)NCC(=O)N[C@@H](CO)C(=O)NCC(=O)NCC(=O)NCC(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

Hae Cells And Nk Cells

Assay & Model

Adult BALB/c mice
Adult BALB/c mice

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L Amphiphilic
Synthetic
GFP protein. and SpCas9 or AsCas12a ribonucleoprotein (RNP)
Nucleus
In vitro and in vivo
CHHHHHHHHHHHTTTCCTTTTCCCCCSCSSCC
Additional Detail Fields 1 fields
CHHHHHHHHHHHTTTCCTTTTCCCCCSCSSCC