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Peptide record

TPDB62979

PN202 (SEQ ID NO: 50) Cell-penetrating Peptides standard
33 amino acids
Basic Information
3D PDB MODEL
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TPDB62979
PN202 (SEQ ID NO: 50)
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CellPPD CellPPD-MOD CPPsite3.0 MLCPP 2.0 Peptipedia PerseuCPP
standard
No
A 33-aa standard natural cell-penetrating peptides peptide sequence curated from CellPPD, CellPPD-MOD, CPPsite3.0, and other sources, with an available 3D structural model.
C-terminal: Amidation
Sequence
LLETLLKPFQCRICMRNFSTRQARRNHRRRHRR-NH2
Physicochemical Analysis
C179H306N72O43S3
DGWYV
R
4251.04
12.58
13
1
9
+10
10.20
-1.291
62.12
Mammalian: 5.5 hour Yeast: 3 min E.coli: 2 min
125
2.94
9
Residue Composition
number
1
A
10
R
2
N
0
D
2
C
1
E
2
Q
0
G
2
H
1
I
4
L
1
K
1
M
2
F
1
P
1
S
2
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 1 R: 10 N: 2 D: 0 C: 2 E: 1 Q: 2 G: 0 H: 2 I: 1 L: 4 K: 1 M: 1 F: 2 P: 1 S: 1 T: 2 W: 0 Y: 0 V: 0
Chemical Descriptors
33
C179H306N72O43S3
4251.04
12.58
+10
10.20
-1.291
Amidation
L
Linear
Free
N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CS)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CS)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CO)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CC1=NC=NC1)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CC1=NC=NC1)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

9 L/LacZ cells

Source & Reference

CPPsite3.0
CPPsite3
US 20060035815

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Synthetic
Nucleic acid (siRNA)
In vitro
CGGGTCCTTTTCCCSSSSSCTTTTTCSCSCC
Additional Detail Fields 1 fields
CGGGTCCTTTTCCCSSSSSCTTTTTCSCSCC