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Peptide record

TPDB62967

PPC2 Cell-penetrating Peptides standard
17 amino acids
Basic Information
3D PDB MODEL
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TPDB62967
PPC2
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 17-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
Sequence
LKKRRKLPKKKPIRNEQ
Physicochemical Analysis
C96H178N34O22
ADCGHMFSTWYV
K
2160.68
12.18
9
1
3
+8
10.86
-2.265
68.82
Mammalian: 5.5 hour Yeast: 3 min E.coli: 2 min
0
0.00
2
Residue Composition
number
0
A
3
R
1
N
0
D
0
C
1
E
1
Q
0
G
0
H
1
I
2
L
6
K
0
M
0
F
2
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 3 N: 1 D: 0 C: 0 E: 1 Q: 1 G: 0 H: 0 I: 1 L: 2 K: 6 M: 0 F: 0 P: 2 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
17
C96H178N34O22
2160.68
12.18
+8
10.86
-2.265
Free
L
Linear
Free
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

HeLa 654 cells

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Non-natural residues Linear L
Synthetic
PMO and Cy5.5 dye
Increased fluorescence by more than 3-fold
Macropinocytosis
In vitro