Back to search

Peptide record

TPDB62960

LK‐6 Cell-penetrating Peptides standard
109 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB62960
LK‐6
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 109-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
Sequence
LKKLLKLLKKLLKLGGLKKLLKLLKKLLKLAGGSEFLKKLLKLLKKLLKLGGLKKLLKLLKKLLKLAGKSSDPNSSSLKKLLKLLKKLLKLGGLKKLLKLLKKLLKLAG
Physicochemical Analysis
C584H1083N147O121
RCQHIMTWYV
L
12100.93
11.56
37
2
52
+35
13.11
0.233
174.50
Mammalian: 5.5 hour Yeast: 3 min E.coli: 2 min
0
0.00
7
Residue Composition
number
3
A
0
R
1
N
1
D
0
C
1
E
0
Q
10
G
0
H
0
I
48
L
37
K
0
M
1
F
1
P
6
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 3 R: 0 N: 1 D: 1 C: 0 E: 1 Q: 0 G: 10 H: 0 I: 0 L: 48 K: 37 M: 0 F: 1 P: 1 S: 6 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
109
C584H1083N147O121
12100.93
11.56
+35
13.11
0.233
Free
L
Amphipathic
Hexamer
Free
N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)NCC(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

HeLa and HEK 293T cells

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Hexamer L Amphipathic
Synthetic
TAMRA dye and Enhanced green fluorescence protein (eGFP)
Cytosol and Nucleus
Same as LK‐4–eGFP.
In vitro
CHHHHHHHHHHHTTCC
Additional Detail Fields 1 fields
CHHHHHHHHHHHTTCC