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Peptide record

TPDB62945

EB-1 Cell-penetrating Peptides standard
26 amino acids
Basic Information
3D PDB MODEL
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TPDB62945
EB-1
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0 Peptipedia
standard
No
A 26-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0 and Peptipedia, with an available 3D structural model.
Chemical: Linker Di-Glycine
Sequence
LIRLWSHLIHIWFQNRRLKWKKKGGC
Physicochemical Analysis
C157H246N48O30S1
ADEMPTYV
LK
3318.04
12.16
9
0
11
+7
-0.63
-0.492
105.00
Mammalian: 5.5 hour Yeast: 3 min E.coli: 2 min
16500
497.28
4
Residue Composition
number
0
A
3
R
1
N
0
D
1
C
0
E
1
Q
2
G
2
H
3
I
4
L
4
K
0
M
1
F
0
P
1
S
0
T
3
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 3 N: 1 D: 0 C: 1 E: 0 Q: 1 G: 2 H: 2 I: 3 L: 4 K: 4 M: 0 F: 1 P: 0 S: 1 T: 0 W: 3 Y: 0 V: 0
Chemical Descriptors
26
C157H246N48O30S1
3318.04
12.16
+7
-0.63
-0.492
Free
Linker Di-Glycine
L
Amphipathic
Linear
Free
N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC1=C(C(=NC1)C)CC)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC1=NC=NC1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC1=NC=NC1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC1=CN=C(C)/C/1=C\C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC1=CN=C(C)/C/1=C\C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)NCC(=O)N[C@@H](CS)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

HT-29-luc cells

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L Amphipathic
Synthetic
PNA
Endocytosis
In vitro
CCTTTCCCSSSCCCCCSSSSCSCC
Additional Detail Fields 1 fields
CCTTTCCCSSSCCCCCSSSSCSCC