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Peptide record

TPDB62940

Transp-FIT_PNA1 Cell-penetrating Peptides standard
28 amino acids
Basic Information
3D PDB MODEL
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TPDB62940
Transp-FIT_PNA1
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 28-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
N-terminal: Acetylation
Sequence
Ac-LIKKALAALAKLNIKGLLYGASNLTWGC
Physicochemical Analysis
C137H231N35O34S1
RDEQHMFPV
L
2944.61
10.31
4
0
16
+4
-3.32
0.700
143.21
Mammalian: 5.5 hour Yeast: 3 min E.coli: 2 min
6990
237.38
6
Residue Composition
number
5
A
0
R
2
N
0
D
1
C
0
E
0
Q
3
G
0
H
2
I
7
L
4
K
0
M
0
F
0
P
1
S
1
T
1
W
1
Y
0
V
Amino Acid Distribution
A: 5 R: 0 N: 2 D: 0 C: 1 E: 0 Q: 0 G: 3 H: 0 I: 2 L: 7 K: 4 M: 0 F: 0 P: 0 S: 1 T: 1 W: 1 Y: 1 V: 0
Chemical Descriptors
28
C137H231N35O34S1
2944.61
10.31
+4
-3.32
0.700
Free
L
Linear
Acetylation
N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)NCC(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC1=CN=C(C)/C/1=C\C)C(=O)NCC(=O)N[C@@H](CS)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

Hek293 Cells

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
FIT-PNA1
Cytosol
In vitro
CCHHHHHHHHHHSCSSSCCCSCCSCCCC
Additional Detail Fields 1 fields
CCHHHHHHHHHHSCSSSCCCSCCSCCCC