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Peptide record

TPDB62917

Tat (43-60) Cell-penetrating Peptides modified_plain modified
18 amino acids
Basic Information
3D PDB MODEL
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Sequence-matched coordinates; source-recorded chemical modifications are not verified in this model.

TPDB62917
Tat (43-60)
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CellPPD CPPsite3.0 Peptipedia
modified_plain
Yes
A 18-aa modified cell-penetrating peptides peptide sequence curated from CellPPD, CPPsite3.0, and Peptipedia, with an available 3D structural model.
C-terminal: Conjugation with fluorescein maleimide N-terminal: Labelled with Cys-acetamidomethyl
Sequence
LGISYGRKKRRQRRRPPQ
Physicochemical Analysis

Sequence-only estimates are not provided for modified or non-standard source notation. Reported molecular properties, when available, are retained below with their source records.

Chemical Descriptors
18 main sequence record
Conjugation with fluorescein maleimide Activity
L Activity
Cationic Activity
Linear Activity
Labelled with Cys-acetamidomethyl Activity
N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccccc1)C(=O)NCC(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(=O)N)C(=O)O Activity
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

HeLa

Source & Reference

CPPsite3.0
CPPsite3
US 6740524

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L Cationic
Protein derived
Fluorophore (fluorescein)
Cytoplasm and nucleus, nucelolus
High
Non-endocytic mechanism
In vitro
CCTTCCTTTSSCCCCCCC
Additional Detail Fields 1 fields
CCTTCCTTTSSCCCCCCC