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Peptide record

TPDB62915

1788_SpyT Cell-penetrating Peptides standard
48 amino acids
Basic Information
3D PDB MODEL
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TPDB62915
1788_SpyT
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 48-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
Sequence
LFVDKATPQIYYTPSESVTVKSKGKNRRKKSGASAHIVMVDAYKPTKG
Physicochemical Analysis
C236H386N66O69S1
CW
K
5284.12
10.49
11
3
17
+7
12.88
-0.665
62.92
Mammalian: 5.5 hour Yeast: 3 min E.coli: 2 min
4470
84.59
14
Residue Composition
number
4
A
2
R
1
N
2
D
0
C
1
E
1
Q
3
G
1
H
2
I
1
L
8
K
1
M
1
F
3
P
5
S
4
T
0
W
3
Y
5
V
Amino Acid Distribution
A: 4 R: 2 N: 1 D: 2 C: 0 E: 1 Q: 1 G: 3 H: 1 I: 2 L: 1 K: 8 M: 1 F: 1 P: 3 S: 5 T: 4 W: 0 Y: 3 V: 5
Chemical Descriptors
48
C236H386N66O69S1
5284.12
10.49
+7
12.88
-0.665
Free
L
Linear
Free
N1CCC[C@H]1C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(=O)N)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(=O)N)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCN=C)C(=O)NCC(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N[C@@H](C)C(=O)N[C@@H](CC1=NC=NC1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

CHO-K1 Or T47D Cells

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Chimeric
β-lactamase protein and CCF2-AM cell-permeable dye
Cytoplasm
In vitro
CCCSSCCCSEETTEECCCSSCCCCCCCSSCCCCSCCCBCSSSCBCCTTCCSSCC
Additional Detail Fields 1 fields
CCCSSCCCSEETTEECCCSSCCCCCCCSSCCCCSCCCBCSSSCBCCTTCCSSCC