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Peptide record

TPDB62911

Inv10 Cell-penetrating Peptides standard
27 amino acids
Basic Information
3D PDB MODEL
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TPDB62911
Inv10
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CellPPD CPPsite3.0 MLCPP 2.0 Peptipedia
standard
No
A 27-aa standard natural cell-penetrating peptides peptide sequence curated from CellPPD, CPPsite3.0, MLCPP 2.0, and other sources, with an available 3D structural model.
N-terminal: Free (peptide coated FITC labelled microspheres)
Sequence
LDTYSPELFCTIRNFYDADRPDRGAAA
Physicochemical Analysis
C135H201N37O44S1
QHKMWV
AD
3078.36
4.12
3
5
11
-2
4.62
-0.574
58.15
Mammalian: 5.5 hour Yeast: 3 min E.coli: 2 min
2980
96.80
7
Residue Composition
number
4
A
3
R
1
N
4
D
1
C
1
E
0
Q
1
G
0
H
1
I
2
L
0
K
0
M
2
F
2
P
1
S
2
T
0
W
2
Y
0
V
Amino Acid Distribution
A: 4 R: 3 N: 1 D: 4 C: 1 E: 1 Q: 0 G: 1 H: 0 I: 1 L: 2 K: 0 M: 0 F: 2 P: 2 S: 1 T: 2 W: 0 Y: 2 V: 0
Chemical Descriptors
27
C135H201N37O44S1
3078.36
4.12
-2
4.62
-0.574
Free
L
Linear
Free (peptide coated FITC labelled microspheres)
N[C@@H](CC(C)C)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CS)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CCCN=C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CCCN=C)C(=O)NCC(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

HeLa

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Protein derived
Nanoparticle [(FITC)-labeled latex microspheres]
Cytoplasm and nucleus membrane
Low (relative to Inv3)
In vitro
CCTTTTCCSSSCTTTSCCCCSSCTTTC
Additional Detail Fields 1 fields
CCTTTTCCSSSCTTTSCCCCSSCTTTC