Back to search

Peptide record

TPDB62898

Xentry peptides Cell-penetrating Peptides standard
5 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB62898
Xentry peptides
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CellPPD-MOD CPPsite3.0 Peptipedia PerseuCPP
standard
No
A 5-aa standard natural cell-penetrating peptides peptide sequence curated from CellPPD-MOD, CPPsite3.0, Peptipedia, and other sources, with an available 3D structural model.
Sequence
LCLRP
Physicochemical Analysis
C26H48N8O6S1
ANDEQGHIKMFSTWYV
L
600.78
9.01
1
0
2
+1
-0.10
0.800
156.00
Mammalian: 5.5 hour Yeast: 3 min E.coli: 2 min
0
0.00
1
Residue Composition
number
0
A
1
R
0
N
0
D
1
C
0
E
0
Q
0
G
0
H
0
I
2
L
0
K
0
M
0
F
1
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 1 N: 0 D: 0 C: 1 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 2 K: 0 M: 0 F: 0 P: 1 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
5
C26H48N8O6S1
600.78
9.01
+1
-0.10
0.800
Free
L
Linear
Free
N[C@@H](CC(C)C)C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCN=C)C(=O)N1CCC[C@H]1C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

HepG2, WM-266-4 and BT549

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Protein derived
Fluorophore (FITC- and TAMRA)
Cytoplasm and nucleus
Higher uptake efficiency
Probably Clathrin mediated endocytosis and is dependent on HSPG-decorated syndecan-4
In vitro
CCCCC
Additional Detail Fields 1 fields
CCCCC