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Peptide record

TPDB62886

D4 Cell-penetrating Peptides modified_plain modified
6 amino acids
Basic Information
3D PDB MODEL
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Sequence-matched coordinates; source-recorded chemical modifications are not verified in this model.

TPDB62886
D4
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
modified_plain
Yes
A 6-aa modified cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
Chemical: Liquid crystalline nanodispersion (LCN)
Sequence
LARLLT
Physicochemical Analysis

Sequence-only estimates are not provided for modified or non-standard source notation. Reported molecular properties, when available, are retained below with their source records.

Chemical Descriptors
6 main sequence record
Free Activity
Liquid crystalline nanodispersion (LCN) Activity
L Activity
Cationic Activity
Linear Activity
Free Activity
N[C@@H](CC1=C(C(=NC1)C)CC)C(=O)N[C@@H](CC1=CN=C(C)/C/1=C\C)C(=O)N[C@@H](CC1=C(C(=NC1)C)CC)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CC1=C(C(=NC1)C)CC)C(=O)N[C@@H](CC1=C(C(=NC1)C)CC)C(=O)N[C@@H](CC1=CN=C(C)/C/1=C\C)C(=O)O Activity
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

A431 Cells

Assay & Model

Male hairless mice (HRS/J, 4–6 weeks old)
Male hairless mice (HRS/J, 4–6 weeks old)

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L Cationic
Synthetic
Lipoic acid (LA)
Cytoplasm
3-fold higher penetration compared with LCN-FITC
In vitro and in vivo
CCCCCCCCCC
Additional Detail Fields 1 fields
CCCCCCCCCC