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Peptide record

TPDB62885

(LARL)3 Cell-penetrating Peptides standard
12 amino acids
Basic Information
3D PDB MODEL
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TPDB62885
(LARL)3
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 12-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
Chemical: Gold nanocarrier N-terminal: Conjugated with 6-Carboxyfluorescein (6-Fam)
Sequence
LARLLARLLARL
Physicochemical Analysis
C63H119N21O13
NDCEQGHIKMFPSTWYV
L
1378.77
12.70
3
0
9
+3
-1.44
1.225
220.00
Mammalian: 5.5 hour Yeast: 3 min E.coli: 2 min
0
0.00
0
Residue Composition
number
3
A
3
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
6
L
0
K
0
M
0
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 3 R: 3 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 6 K: 0 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
12
C63H119N21O13
1378.77
12.70
+3
-1.44
1.225
Free
Gold nanocarrier
L
Amphiphilic
Linear
Conjugated with 6-Carboxyfluorescein (6-Fam)
N[C@@H](CCCCN)C(=O)N[C@@H](CC1=NC=NC1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC1=NC=NC1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC1=NC=NC1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1[nH]cnc1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC1=NC=NC1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC1=NC=NC1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC1=NC=NC1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1[nH]cnc1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1[nH]cnc1)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCSC)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

Onion Bulb Scales

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L Amphiphilic
Synthetic
FAM dye
Mitochondria
(LARL)3 showed a dispersed fluorescence with a relatively stronger intensity in Mitochondria.
In vitro
CCSCSCCSCSTTHHHHSCC
Additional Detail Fields 1 fields
CCSCSCCSCSTTHHHHSCC