Back to search

Peptide record

TPDB62871

VP2-2 (CPP4) Cell-penetrating Peptides standard
13 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB62871
VP2-2 (CPP4)
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 13-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
Sequence
KYWWKNLKMMIIL
Physicochemical Analysis
C87H135N19O16S2
ARDCEQGHFPSTV
K
1767.27
10.46
3
0
9
+3
-3.45
0.162
120.00
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
12490
706.74
2
Residue Composition
number
0
A
0
R
1
N
0
D
0
C
0
E
0
Q
0
G
0
H
2
I
2
L
3
K
2
M
0
F
0
P
0
S
0
T
2
W
1
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 1 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 2 L: 2 K: 3 M: 2 F: 0 P: 0 S: 0 T: 0 W: 2 Y: 1 V: 0
Chemical Descriptors
13
C87H135N19O16S2
1767.27
10.46
+3
-3.45
0.162
Free
L
Linear
Free
N[C@@H](CC(=O)N)C(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](Cc1[nH]cnc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(C)C)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

B16-F10 Cells , PC-12 Cells ,B16-F10 And Human Dermal Fibroblasts (Hdfs)

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Protein derived
FITC at N terminal
CPP-4 displayed the highest cellular uptake at 15.3%
In vitro
CCCCCCCCTTC
Additional Detail Fields 1 fields
CCCCCCCCTTC