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Peptide record

TPDB62868

TDb-1 (CPP8) Cell-penetrating Peptides standard
13 amino acids
Basic Information
3D PDB MODEL
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TPDB62868
TDb-1 (CPP8)
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 13-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
Sequence
KYIVTNWLAKVNT
Physicochemical Analysis
C73H116N18O19
RDCEQGHMFPS
NKTV
1549.83
10.20
2
0
7
+2
-0.59
0.008
112.31
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
6990
451.02
5
Residue Composition
number
1
A
0
R
2
N
0
D
0
C
0
E
0
Q
0
G
0
H
1
I
1
L
2
K
0
M
0
F
0
P
0
S
2
T
1
W
1
Y
2
V
Amino Acid Distribution
A: 1 R: 0 N: 2 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 1 L: 1 K: 2 M: 0 F: 0 P: 0 S: 0 T: 2 W: 1 Y: 1 V: 2
Chemical Descriptors
13
C73H116N18O19
1549.83
10.20
+2
-0.59
0.008
Free
L
Linear
Free
NCC(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

B16-F10 Cells , PC-12 Cells ,B16-F10 And Human Dermal Fibroblasts (Hdfs)

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Protein derived
FITC at N terminal
CPP-8 displayed the highest cellular uptake at 91.8%
In vitro
CCCCCCCSCC
Additional Detail Fields 1 fields
CCCCCCCSCC